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Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs and alcohol consumption. Importance of avoiding alcohol while taking the drug.Slow IV injection is essential, and patients should be carefully observed during administration. This requires that blood pressure, respiration, and cardiac function be maintained, vital signs be recorded, and equipment for resuscitation and artificial ventilation be available. The rate of IV injection should not exceed 50 mg/min for pentobarbital sodium.
Studies Durante laboratory animals have shown that barbiturates cause reduction Durante the tone and contractility of the uterus, ureters, and urinary bladder. However, concentrations of the drugs required to produce this effect Durante humans are not reached with sedative-hypnotic doses.
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Contraindications to pentobarbital use include prior hypersensitivity reactions to drug use or barbiturate class use. Barbiturates can trigger hypersensitivity reactions by direct histamine release or immunoglobulin E (IgE)–mediated mechanisms and can lead to anaphylaxis.
However, the use of barbiturates as sedatives in the postoperative surgical period and as adjuncts to cancer chemotherapy is well established.
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Some published studies Per mezzo di children suggest that read more similar deficits may occur after repeated or prolonged exposures to anesthetic agents early Per life and may result Sopra adverse cognitive or behavioral effects.
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Adjust anticoagulant dosage as necessary, especially upon initiation or discontinuance of pentobarbital
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If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist click here if you have questions about the best way to throw out drugs.
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Pentobarbital can cause drowsiness and impair mental and physical abilities. Avoid hazardous activities such as driving and operating heavy machinery.